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DESCRIPTION
In the past Ham‘s F12 was the first choice for a serumfree cultivation of CHO-cells and is now substituted through better serumfree systems like our C6000, which is also proteinfree. However it is an appropriate medium for mammalian cells when it is supplemented with FBS. It contains a high concentration of vitamins, amino acids and trace elements. The content of zinc sulphate is increased and it contains putrescine and linoleic acid.
LIQUID MEDIA
| Ham’s F12 Medium |
500 ml |
P04-14550 |
| without L-Glutamine |
|
|
| with 1,176 g/l NaHCO3 |
|
|
| - |
|
|
| Ham’s F12 Medium |
500 ml |
P04-14500 |
| with L-Glutamine |
|
|
| with 1,176 g/l NaHCO3 |
|
|
| - |
|
|
| Ham’s F12 Medium |
500 ml |
P04-14501 |
| with L-Glutamine |
|
|
| without Phenol red |
|
|
| with 25 mM Hepes |
|
|
| with 1,176 g/l NaHCO3 |
|
|
| - |
|
|
| Ham’s F12 Medium |
500 ml |
P04-15500 |
| with stab. Glutamine |
|
|
| with 1,176 g/l NaHCO3 |
|
|
| - |
|
|
| Ham’s F12 Medium |
500 ml |
P04-14559 |
| without L-Glutamine |
|
|
| without Phenol red |
|
|
| with 1,176 g/l NaHCO3 |
|
|
| - |
|
|
| Ham’s F12 Medium |
500 ml |
P04-15600 |
| with L-Glutamine |
|
|
| with 2,5 g/l NaHCO3 |
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|
SPECIAL MEDIA
Minimum order quantity: 20 x 500 ml
| Hams’s F12 Medium |
500 ml |
P04-15700 |
| without L-Glutamine |
|
|
| with 2,5 g/l NaHCO3 |
|
|
| - |
|
|
| Hams’s F12 Medium |
500 ml |
P04-15502 |
| with stab. Glutamine |
|
|
| without Methionine |
|
|
| without Cysteine |
|
|
| with 1,176 g/l NaHCO3 |
|
|
| - |
|
|
| Ham’s F12/IMDM (1:1) |
500 ml |
P04-20950 |
| without L-Glutamine |
|
|
| with 2,1 g/l NaHCO3 |
|
|
| supplemented with: |
|
|
| 7,5 % Foetal Bovine Serum |
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|
| 7,5 % Newborn Calfserum |
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|
| 52,6 mg/l D-Valine |
|
|
| Antibiotics/Antimyotcs admixture |
|
|
| - |
|
|
| Ham’s F12 Medium |
500 ml |
P04-15549 |
| with stab. Glutamine |
|
|
| without Folic acid |
|
|
| with 1,176 g/l NaHCO3 |
|
|
| - |
|
|
| Ham’s F12 Medium |
500 ml |
P04-15548 |
| without L-Glutamine |
|
|
| without Folic acid |
|
|
| with 1,176 g/l NaHCO3 |
|
|
POWDER MEDIA
| Ham’s F12 Medium |
10 L |
P03-4910 |
| without L-Glutamine |
50 L |
P03-4950 |
| without NaHCO3 |
|
|
| - |
|
|
| Ham’s F12 Medium |
10 L |
P03-4110 |
| with L-Glutamine |
50 L |
P03-4150 |
| without NaHCO3 |
|
|
| - |
|
|
| Ham’s F12 Medium |
10 L |
P03-4210 |
| with L-Glutamine |
50 L |
P03-4250 |
| with 25 mM Hepes |
|
|
| without NaHCO3 |
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|
SPECIAL MEDIA
Minimum order quantity: 20 x 500 ml
| Ham’s F12/DMEM (1:3) |
10 L |
P03-9910 |
| with L-Glutamine |
50 L |
P03-9950 |
| without Phenol red |
|
|
| with 7,5 mM Hepes |
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| with 2,075 mg/l Glucose |
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| without NaHCO3 |
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COMPOSITION
|
Components |
mg/L |
| Inorganic Salts |
Calcium chloride anhydrous |
33,30 |
|
Copper(II) sulfate x 5H2O |
0,003 |
|
Iron(II) sulfate x 7H2O |
0,834 |
|
Magnesium chloride x 6H2O |
122,00 |
|
Potassium chloride |
223,60 |
|
Sodium chloride |
7099,00 |
|
di-Sodium hydrogen phosphate anhydrous |
142,04 |
|
Zinc sulfate x 7H2O |
0,86 |
| Other Components |
D(+)-Glucose anhydrous |
1801,60 |
|
Hepes |
5958,00 |
|
Hypoxanthine |
5,46 |
|
Linoleic acid |
0,084 |
|
DL-α-Lipoic acid |
0,21 |
|
Phenol red |
1,20 |
|
Putrescine x 2HCl |
0,16 |
|
Sodium pyruvate |
110,10 |
|
Thymidine |
0,73 |
| Amino acids |
L-Alanine |
8,91 |
|
L-Arginine x HCl |
210,70 |
|
L-Asparagine x H2O |
15,01 |
|
L-Aspartic acid |
13,31 |
|
L-Cysteine x HCl x H2O |
35,12 |
|
L-Glutamine |
146,20 |
|
L-Glutamic acid |
14,71 |
|
Glycine |
7,51 |
|
L-Histidine x HCl x H2O |
20,96 |
|
L-Isoleucine |
3,94 |
|
L-Leucine |
13,12 |
|
L-Lysine x HCl |
36,54 |
|
L-Methionine |
4,48 |
|
L-Phenylalanine |
4,96 |
|
L-Proline |
34,53 |
|
L-Serine |
10,51 |
|
L-Threonine |
11,91 |
|
L-Tryptophan |
2,04 |
|
L-Tyrosine x 2Na x 2H2O |
7,84 |
|
L-Valine |
11,71 |
| Vitamins |
D(+)-Biotin |
0,007 |
|
D-Calcium pantothenate |
0,24 |
|
Choline chloride |
13,96 |
|
Folic acid |
1,32 |
|
myo-Inositol |
18,02 |
|
Nicotinamide |
0,037 |
|
Pyridoxine x HCl |
0,062 |
|
Riboflavin |
0,038 |
|
Thiamine x HCl |
0,34 |
|
Vitamin B12 |
1,36 |
SCHEDULE
|
L-Glutamine |
Stab. Glutamine |
Sodium pyruvate |
Phenol red |
Hepes |
Special |
| 14550 |
|
|
x |
x |
|
|
| 14500 |
x |
|
x |
x |
|
|
| 14501 |
|
|
x |
|
25 mM |
|
| 15500 |
|
x |
x |
x |
|
|
| 14559 |
|
|
x |
|
|
|
| 15600 |
x |
|
x |
x |
|
s.o. |
| 15700 |
|
|
x |
x |
|
s.o. |
| 15502 |
|
x |
x |
x |
|
s.o. |
| 15549 |
|
x |
x |
x |
|
s.o. |
| 15548 |
|
|
x |
x |
|
s.o. |
| 20950 |
|
|
x |
x |
|
s.o. |
Each formulation possible!
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