Endothelial Cell Medium
Endothelial cells line blood and lymph vessels and the internal heart cavities. They have a strongly flattened, polygonal form and mostly rest on a basal membrane (depending on the capillary type). They attach by desmosomes and tight-junctions.
The endothel with a trillion (1012) cells is one of the biggest organs of the body and plays a key role in many physiological and pathophysiological processes (physiological cell-controlled immunoresponse, healing of wounds, inflammation, allergy, cardiovascular diseases, tumour growth, menstruation).
A huge number of soluble factors, which circulate in the blood or are released by neighbouring cells, control proliferation, apoptosis, invasion, migration and leucocyte adhesiveness of endothel cells and regulate for example the regeneration and degeneration of vessels.
ENDOPAN 3 ready-to-use is a specially developed medium for the in vitro culture of human endothelial cells containing all components necessary for optimal growth. It is designed for use in an incubator at 37° C with a 5% CO2 atmosphere.
ENDOPAN 3 kit is provided with FBS and supplements in separate sterile packing. This will enable the user to prepare a medium for special application. For example, FBS, VEGF, FGF-2, or other components may be omitted from the complete medium for specific experimental settings.
HUVEC (Human Umbilical Vein Endothelial Cell) in ENDOPAN 3